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An increased risk for uveitis in patients with psoriasis

An increased risk for uveitis in patients with psoriasis

There is an increased risk for uveitis in patients with psoriasis and an even higher risk for uveitis in patients with psoriatic arthritis. 


These are the conclusions of nationwide study of the Danish population. It was carried out by Alexander Egeberg, MD; Usman Khalid, MD; Gunnar Hilmar Gislason, MD, PhD.  The team confirmed that there is a bidirectional association between psoriatic disease and uveitis.  


The results of the study were published in JAMA Dermatology.


What is the evidence?


Limited evidence is available about the relationship between psoriatic disease and uveitis. The authors claim that this study is the first to examine the bidirectional relationship between psoriatic disease, including psoriasis and psoriatic arthritis, and uveitis.


The study cohort consisted of the entire Danish population 18 years or older starting January 1, 1997, and followed up until December 31, 2011, or until a diagnosis of an end point, migration, or death from any cause. Patients with prevalent psoriasis or uveitis at baseline were excluded. The team identified 74 129 cases of psoriasis and psoriatic arthritis and 13 114 cases of uveitis. 


Increased focus on eye symptoms in patients with psoriasis and psoriatic arthritis and on skin and joint symptoms in patients with prior or current uveitis may be appropriate, the aurthors comment.

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